Hope our descendants enjoy paying for life long drugs to prevent a number of diseases (fingers crossed anyway)
If you’ve ever had someone close to you develop alzheimers, especially family where it was then more likely that you would develop it, you would have no problem paying for drugs to prevent it for life. It’s probably the cruelest thing that can happen to a person in life.
Two of my grandparents had it, I’ll probably get it if I last that long
And would you take a tablet a day to prevent it? As someone in roughly the same situation as you, I’d do it in a heartbeat.
Pretty much depends on the price. If it is over the counter painkiller pricing yes if it is hiv med pricing no
Trump killed over 80% of all Alzheimer’s research, as well as cancer.
Ah, if only Alzheimer’s or cancer would kill him for a change.
Interesting. I had no idea genetic damage was linked to Alzheimer’s disease. Thought it was chance/inherent genetics, a bit like cancer is.
Genetics barely explains 1% of Alzheimer. The problem with Alzheimer dementia, FTD, is that they are likely many causes with a common outcome.
Some AD is caused by diabetes. Some AD is caused by trisonomy 21, Down’s syndrome. Some AD is caused by venous blood restriction.
In later life, the brain accumulates a lot of reactive oxygen species that old mitochondria can’t handle, the result of that oxidation is elevated DNA damage. Some people have efficient DNA repair, some do not. Why? Efficient DNA repair can promote cancer.
In the broad picture of humans, those that avoid cancer are more likely to get AD, an vice versa.
There are genetic forms of early onset Alzheimer’s that run in families. The majority of the cases are not that though. I personally believe the typical cause is a combination of environment and viruses. A similar thing has been happening with bee populations where a chemical weakens their ability to deal with parasites and viruses.
The most recent thing I read is a connection between tires and Alzheimer’s.
https://www.newsweek.com/common-tire-chemical-may-raise-alzheimers-risk-study-finds-12172062
Someone reports a new cause of Alzheimers every week. There is a huge amount of junk science with Alzheimers. At one point, it was picking your nose.
Yes, in the past this has been true. Also, the chemical world is incredibly complex and we have trouble modeling single chemical interactions with the human body let alone multiple. As I mentioned we are seeing latent viruses as the cause of other neurological syndromes like Multiple Sclerosis (from mono) and Parkinson’s (from pegavirus).
The truth is it may be several factors that are exacerbating the ability of these viruses to cause damage and we are still not able to put the pieces of the puzzle together. Part of this is grouping many different possible causes under a single syndrome like we see with genetic Alzheimer’s and environmentally related/viral Alzheimer’s.
I have had the displeasure of working with Alzheimer’s for over a decade. It truly is a horrible disease that steals your loved ones away before you eyes.
This is a mouse model.
I have no idea what is going on at KC London, but they are running to the press with “cures” every month.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10835503/
Safety testing on humans (P1) is complete. No efficacy measures in the study, but that’s not out of the norm for P1.
