Several years ago, I used Blockada, which was frequently recommended. According to some discussion threads, it seems to have fallen from grace.
What ad blocker that doesn’t require root do you use? What’s your experience with it? Would you recommend it?
Does NextDNS use a VPN? Unfortunately TailScale and VPNs can’t be active at the same time
You can actually take it one step further and directly integrate NextDNS into your Tailnet: https://tailscale.com/kb/1218/nextdns/