

Thank you so much for taking the time to explain, I really appreciate it.
Thank you so much for taking the time to explain, I really appreciate it.
Tissue Resident Macrophages hang out in the area of initial infection, waiting for “that guy” to show up again.
This is specifically the bit I’m struggling with. How will they know it’s “that guy”?
It’s a bit like saying “We know this criminal uses disguises. We’ve given everyone copies of his mugshot, which they’ve used for target practice. Now if he wanders in wearing a disguise, people will recognise him.”
As I understand it, “hidden” is a relative thing.
I guess this is the answer?
Going back to my analogy, you’re saying his disguises are pretty simple. So he might wear glasses or a fake beard, but he isn’t likely to turn up in a full clown outfit, with multi-coloured hair, make up, and a big red nose.
This didn’t answer the question for me.
I get the 1st part: They’ve unhidden a stable spike protein hidden by sugars and used it to create an immune response.
The long-term effectiveness is where I’m getting lost. How will the immune system know when to use these particular anti-bodies in the future? If, say, 5 years after being vaccinated I’m infected, surely the relevant spike proteins are hidden by sugars. So how can my body recognise them as the same protein and make more of the correct anti-bodies?
Pannekoek in Afrikaans, pancakes in South African English.
The thick American version we call flapjacks.
Would you mind sharing more details on your experience?
Like, was it a single person that got you thinking, or feedback from a group?
Is there a particular conversation that you remember as the start of change, or rather a gradual shift over time?
Did/was something happen(ing) in your personal life at the time that made you more open to hearing another opinion?