This is sad. Google Play should never hold this much weight in the self hosted community. For Android users dedicated to open source software, F-Droid is the target.

I don’t think SyncThing users would have much issue with the app disappearing from Google. Doing away with Google is the goal.

I spun this up yesterday, because it’s the first viable Google Keep replacement I’ve seen. I love the ability to archive bookmarked pages. And while the web app is clunky for notes (worse UX than Keep), the Android app is a decent replacement. The only weird thing is the option to add notes to notes so you can note while you note.

Worth mentioning that adding or changing a title is completely impossible on Android. Support for titles is included, but hidden, in the web UI, and the web UI adds unnecessary friction to editing notes.

The web UI also doesn’t support newline characters unless they’re preceded by two spaces (strict markdown formatting, like on Lemmy/Reddit), which is annoying. Markdown support is nice, but the vast majority of notes and reminders that I create only require plaintext.

The primary mechanism of action for low-dose rapamycin in longevity is inhibiting mTOR. Reduced inflammation is an important side effect, but mTOR inhibition is the goal. It mimicks fasting, causing cells to ramp up autophagy—a natural process by which organisms recycle half-functioning cells (senescent cells) and use the proteins to build new cells that function properly and don’t produce toxic byproducts.

mTOR inhibition is not the only pathway in cellular metabolism that triggers autophagy, but it’s a major one with a measurable effect.

In simpler terms, inhibiting mTOR by fasting (or by mimicking fasting with intermittent low-dose rapamycin), signals that times are tough and pushes organisms to hunker down for survival. This is good, because it promotes better overall health at a cellular level. The reduction of toxic byproducts from senescent cells is likely a driver of the reduced inflammation that has been observed.

That said, “anti-aging” is a cringey buzzword that hurts the credibility of the field.

Rapamycin has the most promise of any longevity intervention, with over 20 years of research and results that have been reproduced by the NIH.

It’s difficult to fund a clinical trial in humans for this particular use of rapamycin, however, because there is no profit motive for pharmaceutical companies. FDA approval for new uses of an off-patent drug won’t make pharma companies rich. The same problem exists for research on many traditional medicines.

ITT: People who don’t know what they’re talking about

I guess cypherpunk?

That’s probably right. I dunno man, I don’t work here.

There are. There isn’t any difference. It’s like people being afraid of facial recognition for border checks. It’s creepy at first, but governments already have pictures of everyone’s faces from their ID’s. They don’t gain anything from the additional photo except efficiency to speed up a process that’s already in place.

Edit: I will say that I would never want a government app directly linking my ID to my phone unless I could be absolutely sure it wasn’t doing anything creepy in the background. I wish sandboxing apps was a default feature for all smartphones.

Hal Finney, no?

The software engineer, cryptography expert, and cyberpunk who received the first ever Bitcoin transaction and had a neighbor named “Dorian Satoshi Nakamoto”?

Whoosh

Edit: My point was that a couple of kids doing this on a small scale pales in comparison to Meta’s reach. The students didn’t do anything particularly novel, and Meta, which has a much more comprehensive dataset of faces linked to personal information, personal communications, etc, is already using every means available to do the same thing. The college students simply demonstrated what Meta is already doing on a global scale.

Surely the original “someone” is Meta. Good to have a redundant system I guess /s

This problem desperately needs to be fixed, but the solution isn’t some expensive, over-engineered laser LED matrix. The solution is basic headlights that don’t blind people. You know, like every headlight that existed in the US until a few years ago.

Surely it’s not an insurmountable task to use a cheap LED bulb with the optics to give the beam proper directivity—i.e. not direct the beam into the eyes off oncoming drivers. Maybe even make it replaceable with a screwdriver. Call me crazy.

100%. I subscribe here to learn about new advancements—to learn about technology.

The finances and politics of the tech industry have a home in those respective communities.

What’s controversial about OnlyOffice?

I only recently discovered it, and I’ve been happy with it so far. I’ve found the interface a little more snappy and easy to use than LibreOffice.

Nah, condoms have existed for ages and have many other benefits.

FTFY

Not sure what buying a short form video platform has to do with creating a new internet dedicated to privacy and open protocols, but cool? Maybe he just wants the user base

Who exactly was hyped about this?

Personally, I typically want my interactions with technology to be quiet. I don’t want it talking, and I don’t want to be talking to it.

Not to mention the privacy implications of an always-on camera and microphone connected to the internet

This sounds like the open source LLM community

I don’t think anyone in this thread thinks it’s good for any government to be spying on everyone. But if we can cut off that flow of data to at least one government, great. Especially since that government is oppressive and authoritarian.

Maybe one day the US government will be cut off from mass surveillance as well.

In terms of reciprocity, the TikTok ban is long overdue. The US government’s most valuable mass surveillance tools – Google, WhatsApp, Instagram, Snapchat, Facebook, etc – aren’t allowed there.

Hah, I would assume they mean not beholden to a government that tracks its citizens with facial recognition, data mines its citizens’ personal communications to arrest them before they can even organize a protest, and is run by a dictator who literally made it illegal to call him Pooh Bear.

The sphere that America exerts control over is not without its issues and is surely corrupt. But it is nowhere near as corrupt, oppressive, and lacking in individual freedom as China and the other contender for world domination. Unlike China, America has no social credit score enforced by an all-seeing mass surveillance mechanism where VPN’s and other attempts to hide from it are strictly illegal. And while many Americans might be racist toward Muslims, the American government does not dehumanize them and force them into labor camps.

Your whataboutism is clearly just a Chinese troll, but I’ll leave this comment as a reminder to others reading that there is zero equivalence.

The best part is that this whole thing is about having the “opportunity” to purchase reddit stock at its IPO price. This user generated content farm wouldn’t dare give away equity for free to users responsible for the site having any past, present, or future value.

I’m not a finance person, but the only gambling I’d do on this company is hope that Wall Street pumps the price post-IPO so I can short it.

My understanding is that the value of each reddit user is priced roughly at $2. A Facebook user is priced at roughly $40. Their only options to maybe be profitable are more enshittification, more users, or both. Or, you know, not paying hundreds of millions of dollars to the execs of an RSS feed with voting and comments.

Great to have this context