Her experience, while not the norm, is far from unusual, experts say.
Applegate disclosed the revelation on an episode of her podcast with Jamie Lynn Sigler, MeSsy, which centers on their lives with MS. (Sigler disclosed that she has relapsing-remitting multiple sclerosis, or RRMS, in 2016.) “In January of 2021, I had numbness in my toes, and that numbness grew to all of my legs,” Applegate recalled on the podcast. “And then the pain started.”


My kid is going through this right now. As a girl, she has the added benefit of “let’s try the pill and see if it helps!”. She has fatigue, heart palpitations and occasional chest tightness (EKG didn’t detect anything, bloodwork all normal with iron on a lower side but not bad). I wonder what would be the recommendation if she were a boy.