US history and US govt are required courses in most high schools. The information they teach is generally what would be on the citizenship test

What do you mean? People watch twitch, why would this be any different?

*we’ll know next month

The pancreas is not really stable enough to be implanted in at all. Other organs you’re imagining like liver, stomach, heart, etc. have a solid lining that can be cut open and stitched back together. The pancreas is more like a cluster of loose cells with veins throughout and held together by a very thin, tissue paper lining. If you try to open it and insert cells, you’re not going to be able to put it back together.

That’s why cells are usually put in the liver, which has a large vein going directly to the pancreas. Close proximity and high blood supply. Implanting in the pancreas will likely never be an option unless you can drastically reduce the volume of cells.

Our lab was working on implanting the stem cells on a porous scaffold in the fat pad of the stomach as an alternative

Unfortunately, that doesn’t necessarily negate the requirement for immunosuppresors or some other kind of immuno protection. If it is Type 1 diabetes, the person originally became diabetic because the immune system saw certain markers on the beta cells (insulin producing cells) as a threat. So, if you recreate the beta cells, there is still a possibility that it will happen again. You are fighting your own immune system. Someone in our lab was studying encapsulation of cells to create a protective barrier around them for this very issue

If the person was Type 2, this might be less of a risk since type 2 can also be due to high insulin resistivity. There are a lot of other factors involved, though, it’s not straightforward

I literally worked in a research lab working on islet cell therapies for diabetes in the US. This has actually been done many times before with cells from cadavers. It has been successful, although most the of the time the person reverts back after a few years

The issues we were trying to solve in the lab were

1. Finding a good place to transplant where the cells will last: Implanting in the hepatic region (liver), which is the most common place to implant, is toxic to the cells over time hence only lasting 3-5 years. The cells need a really good blood supply and the volume you’re transplanting can’t be easily transplanted in the pancreas or kidney capsules (where many successful studies were performed in mice and rats)

2. Being able to consistently make a high volume of stem cells that are fully grown into insulin producing cells: Cadaver cells usually require 3-5 donors for 1 person and require the receiver to be on lifelong immunosuppresors due to the immune response. Depending on the kind of stem cells, the patient may still even need immunosuppresors due to the cell type you’re converting from

All this the say - the article says nothing about where the cells where transplanted, where they came from, or whether the person has Type 1 or Type 2 diabetes. Although it is still a feat, it is likely not the first time it has been done, and we’re still a long ways off from a cure

Dr. Death was about gross negligence in medicine and the failure of the medical system to prevent unqualified doctors from making it through the system. There’s no evidence that this study has anything to do with that

None of those are mammals…

This title really overly praises him for 1) not doing much at all and 2) making changes that should have been made months ago

It’s really inspiring to see such a wide range of hobbies in this thread

If you actually watch the documentary they also talk about 2 pedophiles who were on his set at nick and convicted during that time and one pedophile who was convicted from a disney set.

It’s less about Dan schneider specifically (although he does seem to have a lot of unprofessional, sexist, and inappropriate mannerisms) and more about the need to increase protections for the physical and mental well being of child actors as a whole

The bad part is that their healthcare system still has to deal with the rising number of cases, but it’s not like there has been an unexpected spike from anything unusual

For those who dont feel like reading the whole article, here’s why:

“Much of the increase in kidney failure is caused by an ageing population. When age is taken into account, the number of people with kidney failure as a proportion of the population has remained fairly stable over the past decade, according to data from the registry.”

New fear unlocked

A form of therapy that helps you change behavioral and thought patterns to improve how you feel

Don’t give doctors a bad name like that. They work their asses off to help people and go many years being overworked and underpaid to do it

It’s the insurance companies that reap the benefits of people’s misfortune

If you’re going to get one, highly recommend getting 240V instead of 110v/plug and play type. 240V are the only ones that can really keep up with the heat and give you that real jet feel in the tub.

If possible, keep it somewhere covered. We have it in our covered patio, which allows us to get use of it in any kind of weather and prevents mosquitos/other bugs coming around.

Chemical balancing can be pretty tough, we mostly keep a steady supply of bleach around to make sure it’s staying clean. One issue we had was the test strips never seemed to say the water was hard enough so we kept adding calcium hardner, but it ended up precipitating and making a rough coating on the seats (eventually we were able to clean it off). Ended up deciding it wasn’t a big deal if some values are out of range on the test strips as long as the stuff to keep people safe is balanced (ie chlorine)

I disagree on this one, corn tortillas are really simple if you have a press. The dough is literally just mix masa and water. And to cook them, you just put it on a hot surface for 30 seconds. Meanwhile corn tortillas from the store are always so dry and tasteless, they’re rarely worth buying

A24 is truly a diamond in the rough, everything they make is so unique

It is possible we’re back on the rise. Schafrillas Productions made a great video on youtube discussing how Disney+ is basically shooting themselves in the foot by overextending their brand and fewer people are seeing Disney movies in theaters because you can just wait to see it at home anyways.

But I do think high budget films will never go back to the times of well-intentioned competition where every movie is trying to earn audiences’ hearts. From now on, they will always make movies with less risk and higher profit margins regardless of whether it could be a huge hit or not, because guaranteed money will always win over creative filmmaking