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Joined 1 year ago
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Cake day: June 21st, 2023

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  • We already had the Expanded Access Program (thank you ACT UP) and we don’t want a repeat of thalidomide babies like we had before there were strong protections on how drugs get tested.

    So now we have Expanded Access (EAP) with FDA oversite and Right to Try (RTT) without that oversight. Having both is confusing for everyone and most people don’t know which covers what. From Journal of Law and the Biosciences (they only sampled 17 neuro-oncologists from 15 different academic medical centers):

    Many physicians described having difficulty in distinguishing between RTT and EAP or demonstrated misconceptions in their responses. A physician with knowledge of both pathways spoke about his colleagues generally: ‘I don’t think a lot of people understand the difference between expanded access and Right-To-Try’ [Participant 1]. The confusion resulted in conflation with the different features between EAP and RTT including structure, intent, and processes of these pathways. In response to our question ‘Have you provided a drug through Right-to-Try?’ one clinician erroneously replied, ‘I think most compassionate use is under that category’ [Participant 2]. Another drew a rough equivalence between the two despite the absence of FDA oversight for RTT: ‘I guess the way I try to think about Right-to-Try is like compassionate use.




  • Decades ago, before the internet, when your local radio stations and newspapers paid for service to a special machine that constantly churned out stories from stringers and main branches, there was a saying that I no longer remember but went something like, “Associated Press gets the story first; United Press gets it right.”

    We never doubted that AP/UP/Reu/(etc.) were feeding most the news. The sources were right there in print.

    It is good to remind people that while there are an endless number of websites, most news still comes from a handful of sources. I will even agree that our sources are all biased.

    That said there are some stories where bias should be expected; where there aren’t really two sides. Example: “Locals outraged by villian’s kicking puppies!” Good reporting might include the reasoning, but the public is not going to side with the puppy-kicker. Surely there was a better way to handle the situation before it got to that.

    The public does not side with Hitler, either. Personally, I am thankful that the larger public has been ‘brainwashed’ into thinking Hitler was ‘bad’. It saddens me that there are Nazis (or neo-Nazis) in countries that fought to end that vile cause. The citizenry should know better. More than that, the citizenry should know that all autocrats are bad. Any benevolent dictator is still mortal and will cede the position to someone else, and it won’t be long before the ‘someone else’ is not benevolent.

    So: thank you for posting the link reminding everyone to be critical of all news sources, but also remember that some things are fairly reported. Sometimes a point of view is valid. Sometimes there is an actual solid truth that is being told. Yes, sometimes that truth is getting sensationalized, but that doesn’t it make it less true.

    For this particular case, I will re-iterate that I am worried about potential strife. If my family was living in Venezuela, I would want a stable and well funded government without corruption and without dictatorship. I don’t think the people had that as a ballot option, and I don’t trust any of the players. I do miss Chavez, though. The U.S. gave him a raw deal.




  • I’m anticipating strife and reporting from additional sources. This could get ugly and people should be aware of it.

    Note that al-jazeera itself reported this in the article you linked:

    “Everything we have seen so far indicates the results of the government are just produced,” Phil Gunson, International Crisis Group’s senior analyst for Venezuela, told Al Jazeera. He claimed the tallies announced by the government-controlled electoral authority did not correspond to the votes cast.

    “The result that the opposition claims is the correct one … corresponds very closely to what opinion polls have been saying for the last several months,” Gunson said. “All the partial results we have seen so far indicate the opposition got something like three-fifths of the vote.”


  • Maybe. APnews says:

    Authorities delayed releasing the results from each of the 30,000 polling booths nationwide, promising only to do so in the “coming hours,” hampering attempts to verify the results.

    After finally claiming to have won, Maduro accused unidentified foreign enemies of trying to hack the voting system.

    Per bbc:

    • US Secretary of State Antony Blinken was among those expressing his scepticism after the result was announced by the National Electoral Council, a body which is dominated by government loyalists.

    • The UK Foreign Office also expressed concern over the results

    • The Chilean president, Gabriel Boric, also said he found the result “hard to believe”.

    • Uruguay’s president said of the Maduro government: “They were going to ‘win’ regardless of the actual results.”

    • In a congratulatory message, President Vladimir Putin told Mr Maduro: “Remember, you are always a welcome guest on Russian soil.”

    That said, I didn’t really want Maria Machado “—derided by the Chavista leadership for her pro-market views and her upper-class background“ — to lead a puppet government after getting kicked off the ballot.




  • I had never heard the particular sentence, “I rebuke you in the name of Jesus” as a phrase, but seeing the video, there did not seem to be any hostility in her voice nor actions. The article says:

    In the church, he said, to rebuke is to cast out a demon, or keep a demon from using a person to do something bad. The phrase can be said casually, though, in response to someone’s misbehavior. When Massey says it, her voice is louder and clearer than it has been before, but she doesn’t sound angry. It’s the tone of voice that you might use while saying: For goodness’ sake, this is really getting ridiculous.

    That fits with her actions: totally non-confrontational, but with the mildest of chastisements.


  • The U.S. admission followed a June 14 Reuters investigation that revealed how the Pentagon launched a secret psychological operation to discredit Chinese vaccines and other COVID aid in 2020 and 2021, at the height of the pandemic. As a result of the Reuters investigation, the Philippine Senate Foreign Relations Committee launched a hearing into the matter and sought a response from the U.S.

    According to the June 25 document, Pentagon officials concluded its anti-vax campaign was “misaligned with our priorities.” It says the U.S. military told Filipino officials that operatives “ceased COVID-related messaging related to COVID-19 origins and COVID-19 vaccines in August 2021.”

    … so Trump?

    I imagine Biden had a lot of fires to put out once he became President in January 2021, but it would have been nice if this scheme ended sooner.


  • Saved you a click (I added the bold):

    Also, holding a college degree doesn’t necessarily translate to success in the workplace, Nguyen added, particularly in rapidly evolving fields like technology, where information and skills learned in school can quickly become outdated.

    Other industries in which companies are loosening degree requirements for job candidates include finance and insurance, health care and social services, education, and information services and data, according to Intelligent’s report.

    Some states have even passed legislation to open up job opportunities to applicants without a college degree. In January, Massachusetts Gov. Maura Healey signed an executive order eliminating college degree requirements for more than 90% of state jobs.

    Nearly 60% of business leaders said they removed degree requirements for entry-level positions, while 54% said they did so for mid-level roles and 18% said they did for senior-level roles, according to the survey.

    Personally, I favor requiring a degree for most education jobs – specifically for teaching k-12. First: teachers need to learn how brains develop over time and what the developmental markers are. Second, teacher should learn different methods of learning and teaching to better reach all students. Third, teachers should learn how to create useful tests and what IS a useful test at different age levels. A 2nd grader is not going to write an essay that displays synergistic understanding of two unrelated fields, but a 2nd grader CAN display synergistic learning in other ways. I’ve gone on too long, but you get the idea.






  • He’s already been considering this for at least a week or more.

    He and his team have considered it, but I doubt Trump is capable of preparing for it. His team will try, but – like Biden – he is an old man past his prime. Voters do not want Project 2025, so Trump’s team CAN’T talk about it with anything but denial, and that is the only ‘plan’ they have. The rest is a few insults that Trump repeat over and over, to which Harris can say, “I’ll take the insults if it keeps necessary abortions legal. I’ll take it to keep schools open. To improve them. To make sure [insert message here] is expanded, not abolished.”