Not sure if this is clear. Our bodies are supposed to replace all the cells every 7 or so years. Does that mean the fat too? Or when someone loses 20 year weight, are you getting rid of 20 year old fat?

  • mushroommunk@lemmy.today
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    21 天前

    The 7 year thing is a myth. Howtown has a very good summary on it. 7 year myth some cells are replaced but how often depends on the cell type, some never get replaced.

    When you gain weight your fat cells grow, and when you lose weight they shrink. You don’t actually gain and lose fat cells the way people think. However, the stuff in those cells could very well be old. It’s a complex system and hard to sum up and I’m only friends with the biology people from college but that’s what I understand from them.

    • TheRealKuni@piefed.social
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      21 天前

      When you gain weight your fat cells grow, and when you lose weight they shrink. You don’t actually gain and lose fat cells the way people think.

      But as my doctor explained to me, if they get big enough, they divide. Then even if you lose weight, you have fat cells hanging around who think they should be holding onto more fat than they are. So your body will want to be fat, and will enforce that with cravings.

      It’s why it’s extremely hard to lose a large amount of weight and leave it off. I’m on my third major attempt now.

      • LavaPlanet@sh.itjust.works
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        21 天前

        I’ve heard similar, that your body wants to keep the “norm” whatever that is. And it makes sense that any extreme weight loss, would seem, to your body, that there is a famine or something is wrong and then reset the balance back to what it was, as soon as it can.

        • JandroDelSol@lemmy.world
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          18 天前

          Set point isn’t some magic thing, it’s just the fact that if you eat a consistent diet, you’ll gain/lose weight until your calories in is the same as your calories out. If you’re overweight, you’re eating more than the human body evolved to handle, so your stomach has to expand to accommodate that. When you try and lose weight, you’re usually eating less food, and so your stomach isn’t full and can cause discomfort.

          Losing weight is hard, I get it. I’m working on it myself. But it’s not like your body is working against you. If perceived famine caused people to gain weight, victims of actual famines would be overweight, not skin and bones. It’s not your body against you, it’s the impulsive parts of your brain versus the rational parts.

          • LavaPlanet@sh.itjust.works
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            16 天前

            Yea, but there’s more to it than that. Thyroid causes issues that cause weight to pack on, no matter what your caloric intake is, menopause causing low estrogen causes weight gain because the visceral fat around your organs, the type you can’t exercise off, makes a kinda knock off estrogen, so your body packs on weight, to try and make estrogen there. You could eat one meal a day, all healthy and still put weight on. And there’s so many more health conditions that cause weight gain. Just Genetics, even. The calories in vs calories out theory has been debunked as a singular cause. Sure, if you have no underlying health issues and you watch what you eat, focus on fibre, legumes, vegetables etc, exercise the right amount, you will lose weight, but, if you are able to do that, you are probably already thin. People who are overweight, overwhelmingly have other conditions causing issues, too.

        • incompetent@programming.dev
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          19 天前

          your taste bud’s cravings are the the fault of […] not your body

          Can you cite a reputable source to confirm this? Doesn’t seem right to me.

          • JandroDelSol@lemmy.world
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            18 天前

            i mean, it’s anecdotal, but I crave things that are super unhealthy, like Rally’s fries or ice cream, and I rarely used to crave anything that has real nutritional value. Now that I’ve cut back quite a bit on those, my cravings are starting to return to more healthy options, and right now I would kill for some roasted zucchini.

            in my experience, people are more likely to crave fast food and sweets because they’re literally designed to be addictive. if most people follow their cravings, they aren’t going for the things that provide nutritional benefits, they’re going for the tasty stuff

    • pelespirit@sh.itjust.worksOP
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      21 天前

      the stuff in those cells could very well be old.

      So, losing weight, is like taking a long needed shower for your cells.

      Edit: That link is awesome. Your gut lining turns over every few days and your skin is weeks? That brings up so many more questions about the biome then.

      • mushroommunk@lemmy.today
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        21 天前

        Kind of? The cells, called adipocytes, primarily store triglycerides and a few other things in a liquid form. When you lose weight that liquid gets squeezed out and used as energy, to build other chemicals your body needs, or peed straight out.

        So less a shower and more getting rung out like a sponge.

    • ramble81@lemmy.zip
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      21 天前

      So then I’m curious what happens with liposuction as the fat cells are literally removed. Does your body create more, or no longer store fat, or does it get stored somewhere else?

    • pelespirit@sh.itjust.worksOP
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      21 天前

      It kind of says something different though. It says the amount remains stable, but they’re dying and replacing themselves. It’s quick in fat people and takes longer in lean people.

      It has been generally believed that adult humans cannot create new fat cells. We have thought, until now, that fat cells only and simply increase their fat mass by adding more lipids into fat cells that already exist in order to settle their body weight – this is true, but that is not the end of the story. Research lead by Kirsty Spalding, Jonas Frisén and Peter Arner has recently shown that adult humans constantly produce new fat cells regardless of their body weight status, sex or age.

      Peter Arner, Professor, Department of Medicine, Huddinge, said “The total number of fat cells in the body is stable overtime, because the making of new fat cells is counterbalanced by an equally rapid break down of the already existing fat cells due to cell death.”

      Edit: I can’t wrap my head around this. Why would anyone keep gaining weight then? If the cells are replaced really quickly, why does it get replaced with the exact same amount of weight? It must be from evolution or something, but it’s weird. That means biome, skin, fat, etc, the stuff that replaces itself quickly, keeps the healthy and unhealthy.

      • idiomaddict@lemmy.world
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        21 天前

        From your body’s perspective, fat is insurance. Our bodies aren’t used to excess, so we’re built to accumulate fat whenever we can.

  • zlatiah@lemmy.world
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    21 天前

    From what I remember from nutrition science research… our body fat are literally living, breathing cells. As in, fat cells which specialize into fat storage, which can grow/shrink, and are in fact very metabolically active. So not only do they get replaced over time, they are biologically quite relevant and probably more “active” than, say, the nearby muscle cells

    Wikipedia does have a page for adipocytes, not sure how up-to-date it is but it explains better than I could. Beware that it is quite technical

    • pelespirit@sh.itjust.worksOP
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      21 天前

      Wow, this is something that hasn’t been said. I wonder if this is still current.

      An average human adult has 30 billion fat cells with a weight of 30 lbs or 13.5 kg. If a child or adolescent gains sufficient excess weight, fat cells may increase in absolute number until age twenty-four.[3] If an adult (who never was obese as a child or adolescent) gains excess weight, fat cells generally increase in size, not number, though there is some inconclusive evidence suggesting that the number of fat cells might also increase if the existing fat cells become large enough (as in particularly severe levels of obesity).

      Edit: Also, this explains why some people have it easier and harder

      People who have been fat since childhood generally have an inflated number of fat cells. People who become fat as adults may have no more fat cells than their lean peers, but their fat cells are larger. In general, people with an excess of fat cells find it harder to lose weight and keep it off than the obese who simply have enlarged fat cells.[3]