• Chozo@fedia.io
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    2 months ago

    I’m pretty sure that 90% of all biomass in general contains microplastics these days.

    • davad@lemmy.world
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      2 months ago

      IIRC, there’s a harder, trusted process for measurement. But an easier method that has gained widespread adoption, and that method is what has been called into question.

    • Calfpupa [she/her]@lemmy.ml
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      2 months ago

      This is a hit piece, echoes of big oil & tobacco. It’s picking studies that have (debatable) issues, then is casting a wide net that is encouraging doubt of all microplastics in the body studies. They take the time to explain why these can be ignored, but depend on you to go read the counter-counterarguments made by the original researchers of each study yourself.

      Rauert says there are absolutely nanoplastics in our bodies, but micro plastics are unlikely due to their size.

      It doesn’t do a meta-analysis of all MNP studies and doesn’t disregard bad criticisms or biased voices (Kuhlman). It’s also sensationalised.

      Pulled from a chat about this when this was released

      • e8CArkcAuLE@piefed.social
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        2 months ago

        i’m not too knowledgeable which is why i didn’t bother to read the counter-counter arguments (case solved, problem in between seat and screen). also i didn’t realize it’s a hit piece, by no means would i like to propagate denialism.

        you appear to be way more knowledgeable, do you have more conclusions from that chat? also can you do an eli5 what is meta-analysis?

        • Calfpupa [she/her]@lemmy.ml
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          2 months ago

          My wife is the more knowledgeable one, but a meta-analysis is basically when you combine all the data of similar studies on a subject. It can expose studies that are bad within the data set and better assess the efficacy of the techniques used in a study. Compare that to what was done here, which was mostly just cherrypicking and highlighting the issues of a handful of studies.

          I encourage you to give a peek at the counter counter-arguments! There is some jargon, but there is decipherable stuff in it (moreso than the original papers imo). One of them says something to the effect of “we had to skip the standard control because the control was in a container that was releasing microplastics” which I would consider reasonable.

          I called this a hit piece because the person they quote about it being a “bombshell” works for DOW Chemical.

  • Avicenna@programming.dev
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    2 months ago

    %90 of human tissues probably contain microplastics. title sounds like baity. Is it significantly less or more than other tissues is the question.

    • mic_check_one_two@lemmy.dbzer0.com
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      2 months ago

      The article states that cancerous areas had ~2.5x more microplastics than the surrounding non-cancerous areas. It could be a chicken and egg/correlation≠causation situation, (is cancer caused by microplastics, or do cancerous cells attract microplastics?) but the article does outline that cancer cells clearly had more microplastics.

      • MasterNerd@lemmy.zip
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        2 months ago

        Cancerous tumors tend to siphon more resources than healthy cells. It’s not surprising that they’d have a higher concentration of microplastics

      • Avicenna@programming.dev
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        2 months ago

        It should still be compared to differences in other resources being transported to the tissue, see my answer below. I am not a fan of microplastics, I don’t try to discredit their health effects. It is just that this much information does not help much. I understand that causation would be much harder to prove, but at least one should try to prove for instance that ratio of cancerous to healthy tissue microplastics is much higher than the same ratio other for other stuff that tissues generally transport by blood vessels. This would atleast show that there is an extraordinary relation between the tissue and microplastics in the context of cancer. It could still be causation on the other direction, such as “maybe tissue structure of prostate cancer allows it to absorb microplastics more than other types of resources” but even that would be a useful piece of information.

        • MajorasTerribleFate@lemmy.zip
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          2 months ago

          Potentially, as cancer cells don’t switch off and die the same way, they have a longer lifespan to accumulate microplastics. Especially if the body’s disposal of dead cells actually manages to clear at least some of the microplastics from the body.

  • Tollana1234567@lemmy.today
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    2 months ago

    correlation doesnt equal causation. CANCER cell in general have higher metabolic energy requirements, so they intake more(pump) in the surrouding environment to fuel thier uncontrolled cell division, so naturally microplastics on the outside of the cell would be pumped into the cell along with nutrients it stealing at higher than normal tissue to fuel its growth.

    • lennybird@lemmy.world
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      2 months ago

      https://pmc.ncbi.nlm.nih.gov/articles/PMC12505851/ (October, 2025)

      Microplastics as emerging carcinogens: from environmental pollutants to oncogenic drivers

      ABSTRACT: The widespread environmental pollution of microplastics (MPs) and nanoplastics (NPs) has become a major public health issue, with increasing evidence associating their bioaccumulation with cancer onset. This review offers a thorough examination of the etiological contributions of MPs/NPs in carcinogenesis, clarifying their mechanistic roles in in vitro, in vivo, and patient-derived evidences. Relevant studies were systematically identified and screened following the PRISMA 2020 guidelines to ensure methodological transparency and quality. We highlighted recent discoveries that emphasize the varied accumulation of MPs in several human cancer tissues, including lung, colorectal, gastric, cervical, breast, pancreatic, prostate and penile malignancies. These particles induce harmful biological effects by chronic inflammation, oxidative stress, genotoxicity, disturbance of lipid metabolism, and alteration of the tumor immunological microenvironment. Significantly, MPs/NPs disrupt various oncogenic signaling pathways, particularly NF-κB, PI3K/Akt/mTOR, Wnt/β-catenin, and p53, therefore facilitating tumor initiation, development, and metastasis. In vitro and in vivo studies have corroborated the carcinogenic potential of MPs/NPs, illustrating their capacity to cause cellular transformation, augment metastatic characteristics, and modify drug resistance pathways in cancer cells. Furthermore, the detection of MPs in human biological matrices, including blood, placenta, and tumor tissues, highlights direct human exposure and potential systemic effects. This review emphasizes the mechanistic insights with therapeutic significance, addressing current knowledge gaps in the field. Future research must prioritize biomarker identification, patient-centered investigations, therapeutic targeting, and the formulation of regulatory policies to alleviate the health hazards linked to microplastic exposure. Understanding the intricate relationship between MPs/NPs and cancer biology could facilitate the development of novel cancer prevention and management strategies related to environmental contamination.

      • SaveTheTuaHawk@lemmy.ca
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        2 months ago

        Biased review written out of regional universities in India. These places crank out AI slop every week. All implications, no mechanism.

        • lennybird@lemmy.world
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          2 months ago

          Tbh this comment sounds like biased AI slop. Especially when they detail the mechanisms literally in the abstract.

          Everyone take note their Genetic Fallacy.

    • lennybird@lemmy.world
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      2 months ago

      Notably, tumor tissue contained significantly more plastic. On average, cancerous samples had about 2.5 times the concentration found in healthy prostate tissue (about 40 micrograms of plastic per gram of tissue compared with 16 micrograms per gram).

      Sure, though it’s to be expected that everything contains water in the body. To expect microplastics, however, is kind of different – leaving aside their showing a legitimate difference in microplastic quantity between healthy and unhealthy prostates.

      • TheObviousSolution@lemmy.ca
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        2 months ago

        Correlation still doesn’t prove causation. Tumors process resources different than surrounding cells. The worst thing about the study is that it chooses to focus on microplastics without distinction when we know certain types of plastics have far higher carcinogenic risk than others, it would have just taken than slight bit more effort to actually make it worthwhile.

        • Jyek@sh.itjust.works
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          2 months ago

          Yeah, what if it happens that micro plastics are somehow being trapped in tumors actually removing them from the bloodstream? What if cancer is how we can get the micro plastics out? I’m only half joking here lol. A bleak thought for sure.

        • lennybird@lemmy.world
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          2 months ago

          Naturally, more studies need to be conducted and microplastics have only been intensively studied beginning this past decade (PFAS being separate and longer). Similar to the carnivore fad diet, odds are exceedingly-high that having microplastics is not good for us but long-term and fully causal studies have not fully identified all mechanistic linkages. Yet I recall tobacco industries rhetorically hiding behind these arguments in a similar manner despite growing concerns from scientists and medical professionals.

          I just take issue with the implication of the other user that this is as harmless as ubiquitous and as fearmongering as water. That in itself is absurd.

          Microplastics should not be in our fucking bodies. Water should.

          • TheObviousSolution@lemmy.ca
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            2 months ago

            It shouldn’t, but as a problem it is no longer preventable, at least for most people not able to be born into a socioeconomic bubble now that it has been identified as a problem. Lumping them altogether into microplastics is like lumping all addictive substances - coffee, alcohol, tobacco, marijuana, cocaine - into the same category. Sure, you’d be a lot better not being addicted to anything, but some addictions are worse than others, and for different reasons. It also lumps carcinogenic agents under the same smoke screen as, say, biodegradable microplastics which have considerably lower ecotoxicity.

    • elucubra@sopuli.xyz
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      2 months ago

      You know, I’ve never understood why there are no warning labels on the bottles of the stuff.

  • yabbadabaddon@lemmy.zip
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    2 months ago

    Although this is a scary number, it is worth considering this comes from one hospital and 10 patients. It is a strong hint to pursue research in this area but I wouldn’t call it a proof yet

    • ragebutt@lemmy.dbzer0.com
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      2 months ago

      It’s also worth noting that microplastics appear in basically all body tissue, including the brain, when looking at samples from cadavers in recent years. I don’t remember the name offhand but one study found enough microplastics in the average brain to make a plastic spoon.

      So this might be more of a correlative thing, hopefully. Because the world ain’t stopping with plastic everything

      • MajorasTerribleFate@lemmy.zip
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        2 months ago

        one study found enough microplastics in the average brain to make a plastic spoon

        What the fuck does this mean for Spoon Theory‽

      • yabbadabaddon@lemmy.zip
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        2 months ago

        I don’t know if it is misleading or simply a lack of scientific literacy from the reporter. I can see how the hospital communicated to news outlets to push their findings to get money, and the reporter saw the strong 90% and rolled with it because he doesn’t know better. Or at least I prefer to think this is the reasoning instead of malicious intent.

        • Ikon@sh.itjust.works
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          2 months ago

          If a reporter is reporting on science, scientific literacy is literally their job. Excuses like this allow reports like lions main cures dementia, or x new food is proven to make you live longer. It is explicitly the job of a reporter to know the subject they are reporting on.

          • yabbadabaddon@lemmy.zip
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            2 months ago

            I would tend to agree with you, but I worked a few years as a reporter. The pressure to shit articles as fast as possible, the time constraint and the constant fear of loosing your job sadly does not allow proper reporting. This has a deep impact on society and nobody gives a shit.

  • TheObviousSolution@lemmy.ca
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    2 months ago

    Notably, tumor tissue contained significantly more plastic. On average, cancerous samples had about 2.5 times the concentration found in healthy prostate tissue (about 40 micrograms of plastic per gram of tissue compared with 16 micrograms per gram).

    Still, correlation does not imply causation. It might just be that because of the nature of what tumors are, they get stuck with more microplastics. The biggest problem with this study is that there are known carcinogens in some types of plastics over others, and it seems to outright choose to dismiss any attempt at distinction for the sake of the microplastic boogieman.

  • wpb@lemmy.world
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    2 months ago

    Researchers also found that these fragments appeared in greater amounts inside cancerous tumors than in nearby noncancerous prostate tissue.

    For those who want to give an opinion based on even a smidge more than just the title.

    • sircac@lemmy.world
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      2 months ago

      I am worry about the systematic error treatment of this data, cancer is per se very abnormal in growing parameters…

  • drunkpostdisaster@lemmy.world
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    2 months ago

    Goddamn. This is probably why prostate cancer is sky rocketing. I am pretty sure I got it, but I doubt I can afford to get checked. Wothless fucking life anyway.

    • jaek@lemmy.world
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      2 months ago

      That’s horrible, I’m sorry you’re going through that. Is there not any free way to get it checked out in your country?

      • drunkpostdisaster@lemmy.world
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        2 months ago

        I am trying. But my state is facing heavy brain drain. And honestly it’s taking all I got to even care right now.

        My mom is sick too. She keeps denying it. And wants to visit Hawaii which we have been trying for years to set up and now is our last chance and I simply can’t even live with myself if I let that chance go.

        • Zanathos@lemmy.world
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          2 months ago

          Dr.'s hate this one trick - tell them you’re facing issues peeing and you’ll get recommended to a urologist. Even with my family history of prostate cancer I couldn’t get one until I started having issues with my stream. Sure enough my prostate is slightly enlarged even at 40 and am now on meds for it.

    • NotMyOldRedditName@lemmy.world
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      2 months ago

      I saw someone else in another thread post they weren’t too expensive (relatively) to get checked. I think someone said something like $1500 uninsured in USA, and googles AI answer says on average $2400.

      Not cheap, but it’s not some crazy $20,000 bill kinda thing.

      • AoxoMoxoA@lemmy.world
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        2 months ago

        To me $2400 is some crazy bill kinda thing.

        I’m gonna die soon too I guess , I’d rather not even know at this point. Hope I can figure it out in time to try crack and heroin which are at least somewhat affordable

        • NotMyOldRedditName@lemmy.world
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          2 months ago

          Ya that’s not good for routine checks which is what should be normal, but if you think something is actively wrong its an option, or at least on the lower end of the scale price wise if that’s where you happen to live. That doesn’t count for what happens if its positive and you’re uninsured either.

        • NotMyOldRedditName@lemmy.world
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          2 months ago

          I don’t think that’s true.

          Health insurance is expensive in the US. Many sites indicate an average monthly cost in the $400-$600 range, and given it’s average also means it can be even higher.

          That’s $4800 - $7200 a year, vs a 1 time $2400 if they are in the average cost area for a colonoscopy.

          It’s not great, many people can’t afford that either, but it’s not true that if you can’t afford insurance, you can’t afford $2400

          • michaelmrose@lemmy.world
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            2 months ago

            Pricing is far more complicated with the old having Medicare, many of the poorest having subsidies some free, and others a range of plans mostly at least somewhat subsidized by employers.

            We are a fat unhealthy folk in a country where a single hospitalization can run you 10-100k and financially ruin you due in no small part to cartel pricing.

            So your various medical providers have negotiated given rates for given things that are less special rates and more what you might consider normal pricing whereas if you are not protected by such a “deal” you may pay several times more at hundreds of percent profit for the provider with the expectation that you pay up front for services or die essentially so long as your death isn’t immediately caused by their immediate neglect. Eg you can’t be allowed to actually bleed out for lack of a stitch but you can be allowed to get septic and then be admitted after it’s really too late to do anything but try to bill your family 100k and steal any inheritance from your estate if any.

            So you are incentivized to buy at least the shittiest high deductible plan with an 8000 deductible just to have access to sane pricing, get treated and then billed, and limit max damage if things go bad even if you expect to not actually get much direct benefit. Plus favorable tax treatment paid in.

            Whilst some may choose to risk it being literally incapable of paying a subsidized 100-300 for the shittiest plan possible means that you are poor in a state which doesn’t choose to subsidize the poor and likely illiquid. Most people in America don’t have 2500 to cover am emergency of any variety. This is true of nearly 100% of the bottom half

            Furthermore anyone who needs a colonoscopy needs other things like annual checkups and medication.

            The number of people who can cash pay the sucker uninsured rate but not shitty insurance is basically zero

            • NotMyOldRedditName@lemmy.world
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              2 months ago

              If I’m reading this right, you’re saying there are cheaper insurance options, but the deductible would be so high it wouldn’t cover this $2400 anyway? It’s just more catastrophic things, like if this came back positive and now you needed surgery?

              And ya, even if you have $2400 and think the test is important to take because you have reason to believe you might have it, it doesn’t mean you’d be able to afford the aftercare.

              • michaelmrose@lemmy.world
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                2 months ago

                You are missing the primary part. Without insurance it costs several times more than it would with insurance.

                • NotMyOldRedditName@lemmy.world
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                  2 months ago

                  Not an uninsured colonoscopy, that is the uninsured price on average.

                  Edit: i get youre saying it’d be cheaper if insured, but when talking about this specific thing that is the price.