• zlatiah@lemmy.world
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    5 hours ago

    The “mouse scanner”

    This is way too meta, and somewhat of an inside joke to my previous lab… explanation below

    Explanation

    In cancer biology, many labs work with mice as a model organism. Back in the days before single-cell sequencing and organoids became popular, almost every good lab would routinely graft tumors onto model mice, then inject drugs and other stuff… and after a few weeks harvest the organs. Lots of ppl still do this. Very demanding research but it was state-of-the-art so

    Anyways… my lab, similar to many, used to have scanners for scanning Western Blots (another super common and notorious lab workflow). We’d scan images, histology slides cut from mice organs, etc… We also had a dedicated X-ray or CT machine (probably, memory hazy) specifically for scanning mice organs, but those two are separate

    And one day we were doing journal club and reviewing a cancer biology paper from another lab. They had full-body scans of lots of different mice, nothing too crazy… but in their methods section I think they straight up said they scanned the mice on a scanner 💀

    So yeah, we had this joke of someone putting a still alive mouse on the standard printer-scanner, and then S Q U I S H the mouse to make an image