In an extremely odd case, a single 79-year-old patient was granted early access to Eli Lilly’s powerful, still-experimental obesity drug retatrutide through the Food and Drug Administration’s “compassionate use” program—raising immediate questions if that sole patient is President Donald Trump, according to a report by Stat News.
Lilly’s retatrutide is a highly anticipated next-generation obesity drug that targets GIP and glucagon hormones in addition to GLP-1. It is currently in late-stage trials to treat obesity, diabetes, sleep apnea, and other conditions. Data from a Phase 3 trial that Lilly released in May indicates that patients with obesity (but without diabetes) who took the drug for 80 weeks lost 28 percent of their weight, an amount comparable to bariatric surgery.
Millions of Americans with obesity are eager to get the drug, with options being limited so far to enrolling in a clinical trial or trying to obtain it by dodgy methods.
But according to a barebones public notice and Stat’s sources, a single person has been granted early access through the expanded access, aka “compassionate use” pathway, which is typically used to grant access to patients with a “serious or immediately life-threatening disease or condition” and who are not able to enroll in a clinical trial, often because they are too ill.
The access request was first made in April, when the person was 79 years old (Trump turned 80 on June 14). It was made by a senior clinician at the National Institutes of Health named Ranganath Muniyappa, who requested it on behalf of a patient with refractory obesity, obstructive sleep apnea, and pulmonary hypertension, which is high blood pressure in the lungs. Sources told Stat this patient had spent a year on tirzepatide, a drug that targets the GLP-1 and GIP hormones. But the patient had achieved only moderate weight loss on the drug.
Has he tried copious amounts of injected bleach? Everybody says it works wonders.
There’s a new medical procedure that needs to be done only once. Kinetic injection of lead to the brain. So simple it can be self administered, or with the help of a friend in line of sight.
As a bit of a thought experiment, would it be possible to make a web app the allows users to calculate trajectory based on live weather data and other data points to give people an easy way to fire into the sky and have the lead land accurately near fascists
Might be a fun project.
With a few tweaks Gorillas.bat could accomplish this. I’d do it, but my QBasic coding chops are a little stale.
I hear the russians are especially adept at it. He should ask putin for (more) advice.
Eeplacing mayo on burgers with Ivermectin should also help.
In fact, it will prevent you from ever gaining weight again! Miracle!
If it is, pulmonary hypertension will kill him regardless.
🤞
Not only that, there’s a chance we’ll get to see it. A sudden physical collapse after which he never leaves the hospital is not unlikely.
Thoughts and prayers then.
I’ve got three family members taking this drug and have both lost a ton of weight. All of them have lost sunstantial amounts of weight. My brother is down 70 pounds.
Ain’t no way Trump is taking it. He’s still fat as shit.
The drug works by killing your appetite. Trump’s a long-time abuser of amphetamines, which do the same thing. His current obesity means a reduction in appetite did nothing for him, which is probably why the previous anti-obesity drugs also failed.
As far as we know all he eats is McDonald’s so is anyone surprised?
trump is immune to constipation due to the drug abuse.
seems like overeats/addicted, GLP-1 likely would work on that.
He can’t resist Whoppers.
Do any of your family members eat McDonald’s 3 times a day and only sleep 4 hours a night?
They used to.
remember also large diet sodas too.
He’s lost 70 lbs in morals and human decency.
Enigmas never age, have you noticed that?
It’s probably not him: he’s still a lardass.
That’s the point, apparently he tried other weight loss drugs and they didn’t work. I guess his addiction to McDonald’s is stronger than Ozempic.
with today’s drugs, maybe it’s “twice as good as the leading competitor” meaning it helps 0.2% instead of just 0.1%
retardutide?
The patient’s name? John Baron
It would be extremely funny if he cheated his way to early entry, and then it turns out it isn’t safe for old fucks. Like maybe that hasn’t been tested since it’s still early enough in trials.
retatrutide
I had to do a double take to make sure it was retardicide… That surely would have gotten rid of the fucker
Let’s pray for non trivial side effects. And I’m not even religious
He really could use a retatrutide adjustment.
Nah, just let the cholesterol do its thing.
I don’t think we’re supposed to say ‘retatrutide’ any more (it’s ableist)
Just imagine how much more disgusting he would look if he lost 50-100 pounds and he was a shambling pile of loose skin.
Turns out the wicked witch of the west was orange; not green…
I’d prefer Raiders of the Lost Ark to The Wizard of Oz in this specific case.
like one of those zombies that had all the fat and flesh rot out, but their skin… sun tanned and dried, hangs on, like some kind of moribund hipster fashionista bag.
Question for someone who knows more about GLP-1 drugs than myself - if you’re taking the drug regularly, and you’re also self-administering a medicinal Whopper and large fries >1x per day, will you still lose weight? The stuff works but thermodynamics still applies?
The class of drugs works by suppressing appetite. So you just eat less and feel good about it. Which makes restaurant chains very, very nervous.
They should just charge more for less amount of tastier food.
testier food
Personally I’m not a fan of the thought of eating testes. There are markets for it, but do you think this has the required mass market appeal to save the chains?
Haha typo
Been on a GLP-1/GIP compounded injection for a year. Lost 90lbs.
I physically have a hard time overeating on fats/protiens. Like I want to vomit. Meat consumption is way down from before.
Simple carbs like starches and sugar I can overinduldge on but seem to get sick faster than before taking the medication.
It mostly helps with food related cravings but its not a silver bullet. I can still fallback to emotional eating under high stress and fluctuate +5 lbs with water retention. Its just much easier to recover.
I lost about 1/3 the weight on my own tracking everything. With the medication it tripled the rate of loss and I didn’t need to track anymore. I’m much more able to trust my body and hunger signals developing a healthier relationship with food.
That’s awesome on the 90 lbs. And interesting on how it seems to operate. Almost like it de-programs one from addiction to sweets and big portions.
probably also suppressing his cocaine and adderal addiction too.
He needs dementia drugs more.
Hmm. Public notice appears to be unavailable…
