• i_have_no_enemies@lemmy.worldOP
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    1 year ago

    my dad is refusing to take vaccines because he thinks taking it will automatically make him vote dem because of nano-machine in them.

    he also thinks vaccines are kind of HRT.

    anyways how’s your day?

    • Pons_Aelius@kbin.social
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      1 year ago

      I hope you are an adult and no longer live with your parents.

      If that is the case remember this. If you cannot have pleasant encounters with him, you are under no obligation to have them at all.

      • Kecessa@sh.itjust.works
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        1 year ago

        No obligation to keep seeing them, would be kind of hard not to have parents 😛

            • Pons_Aelius@kbin.social
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              You sound like you have a good relationship with your parents, many don’t.

              You can be there for them when they need you without putting up with the anti-vax ravings you mentioned. It is called setting boundaries.

              You do what you think is right but also understand that is not a universal thing for all people.

              • i_have_no_enemies@lemmy.worldOP
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                1 year ago

                You sound like you have a good relationship with your parents

                not really.

                i think it is best to minimize contact but not keep null, since these kind of people are self destructive.

                that’s the only reason i stayed , for their health issues.

                • mild_deviation@programming.dev
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                  1 year ago

                  What about your health? Your mental health in particular.

                  Your parents raising you is not something you owe them for. You didn’t choose to exist; they chose that for you. Raising you is the bare minimum they can do after making a choice like that. And now that you are older, you can reflect on the manner in which you were raised and decide what your relationship with them needs to look like so you can keep your sanity.

            • Rbnsft@lemm.ee
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              1 year ago

              Nope they chose to get a child. You dont have to Do anything for them.

        • Mac@mander.xyz
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          1 year ago

          The “them” in that sentence refers to “encounters” not “parents”.

    • Kaavi@lemmy.world
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      1 year ago

      I watched birds are not real Ted talk the other day, I think it was awesome to give a perspective on the conspiracy stuff and how people run with it.

      If it flies, it spies. 🐣

  • deranger@sh.itjust.works
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    1 year ago

    While I’m sure there is a crazy markup, it’s important to note the cost to produce - as in manufacture - does not include the cost of drug discovery, which is extremely expensive and involves a good amount of risk over a long period of time.

    You can’t just compare the cost of discovering a new drug vs. cost of producing a generic without any research like that.

    • be_excellent_to_each_other@kbin.social
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      1 year ago

      https://jacobin.com/2023/09/big-pharma-research-and-development-new-drugs-buybacks-biden-medicare-negotiation

      Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs

      While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.

      • repungnant_canary@lemmy.world
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        1 year ago

        I like Lemmy for exactly this - whenever someone incorrect makes a statement they’re factchecked.

        Thank you kind person for finding and sharing that source.

        • flawedFraction@lemmy.world
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          OP didn’t make an incorrect statement though. What they stated was an important part of the equation. I think a lot of people don’t take that type of thing into account and they will read what this post says and assume that Pfizer should be charging $13, or maybe something pretty close like 15 or 20. Clearly 1400 is far far too high, 13 is too low. A reasonable price allows the manufacturer to be successful while not gouging consumers lies somewhere in between, but much much closer to the low end than the high. To me that’s really what the person you are responding to is giving evidence for.

    • Nate Cox@programming.dev
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      R&D on drugs is insanely expensive, but the protections put in place with the pricing are also a bit absurd. Most drug companies will lock down the formula for a period of time and price the drug aggressively for a short time (like a few years) and then open the formula up to generics who buy it and sell the same damn thing for a fraction of the cost.

      For clarity I’m agreeing with you that the price is largely due to non-manufacturing costs and the article is misleading as a result, but I also wanted to say that the whole industry is a testament to capital over humanity.

    • clausetrophobic@sh.itjust.works
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      1 year ago

      Fuck off with the big pharma apologetics.

      Boo hoo the corporation got millions in taxpayer money to develop a vaccine and now they have to profit off of it. I feel so bad for them.

      This is subtle astroturfing.

      • RBG@discuss.tchncs.de
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        1 year ago

        Guess this comment of mine will also get deleted but here goes nothing.

        The article is about antiviral medicine, not a vaccine. So you are getting angry at the wrong thing.

      • LufyCZ@lemmy.world
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        1 year ago

        Are we talking about the vaccine here? Sounds like a post-exposure drug to me

    • Sprokes@lemmy.ml
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      That’s just an excuse because many drugs are sold at prices much lower what they are sold in the US. They are not selling them at loss in other countries.

      • LufyCZ@lemmy.world
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        Definitely not at a loss to produce no, but maybe a loss overall.

        My bet is that the US subsidizes R&D by paying obscene amounts for the drugs and the EU and others just serve as extra income

        • Sprokes@lemmy.ml
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          That’s what they make you believe. Why American still pay high prices for insulin? It doesn’t cost that much to produce. It just those companies are paying politicians to keep things in their advantages and give you those excuses.

      • RBG@discuss.tchncs.de
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        Well here you go again when people with no scientific education pull up literature as a gotcha. Thanks for giving me flashbacks to the high times of the pandemic. Sorry for the harsh reply but its posts like this that just funnel into misinformation around this already heavily polarized topic.

        To explain, Paxlovid is not a vaccine, it is an actual medicine/treatment. So it was not funded by taxpayers as the article states. Unless there is some other info on how this specific medicine was also funded by taxpayers of course, I am not an expert on research funding. But the article only mentions vaccine research.

        That said, I also do not think its a fair price necessarily. But it is true one should not equate production price as a fair price as R&D of drugs have high costs, mostly also because a lot of drug programs fail, making all prior investment to them a loss.

    • SuckMyWang@lemmy.world
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      Yes we can. It’s just doesn’t give a good faith assessment of the situation. And why would I want to do that if it’s counter to my rigid world view? sigh better add an /s

  • RVMWSN@lemmy.ml
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    Intellectual property is a scam. A commonly heard defense of intellectual property is that it is needed for companies to fund their R&D. However pharmaceutical companies typically spent a lot more money on marketing & sales than they do on R&D. Big Pharma spending money on marketing and sales is harmful to our health. Apparently it’s a lot more lucrative to get people drugged up on painkillers or whatever than to discover new medicine. If we didn’t have intellectual property then we would have competition resulting in the lowest possible medicine prices. Companies would have no money for marketing so medicine would be judged on their actual properties, only the best would be given to patients, not the best marketed, but best health-wise. Companies would have no money for R&D either, but the government could fund R&D We shouldn’t blame the players, we created a system that produces these bad actors. Let’s change the system so that these bad actors couldn’t exist. Intellectual property is a international problem, join the pirate party of your country and let’s make it happen!

      • piecat@lemmy.world
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        There is some level of R&D they do to productize it, manufacturability and scaling. And running drug safety trials cannot be cheap, especially the liability insurance.

        That all said, I think it’s criminal that the university labs pay so little. PhD students barely make over $40k, set by the NIH. Not adjusted for CoL either.

        I think I have more of an issue with the for-profit nature of pharma companies. Shareholders shouldn’t be involved in medicine.

      • Pyr_Pressure@lemmy.ca
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        The woman who got the nobel prize for the mRNA research that led to the Pfizer vaccine did a lot of it while employed at Pennsylvania University before they fired her because they didn’t see the research leading to making them money. Then she moved on to Biontech where she continued the research.

        I’m not sure how much was done at the university but it was probably not insignificant and then biontech got lucky and snapped it up for basically free.

    • uis@lemmy.world
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      AFAIK some US agency did R&D for COVID, they just bribed sponsored Right People

  • anon_8675309@lemmy.world
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    1 year ago

    Didn’t the government fund the development? So… it’s not like they need so much to recover R&D right?

    • Isakk86@lemmy.world
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      Welcome to the United States. Everything is subsidized, then turned around to fuck the average person.

    • MirthfulAlembic@lemmy.world
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      The government did not for Pfizer. That was Moderns. Pfizer did spend billions of their own cash. This move is largely because the executive leadership way overestimated the amount of covid vaccine and drug treatment revenue for this year, and they are desperate to make up ground.

      So they are raising prices and cutting across the board rather than admitting they didn’t know what they were doing in their projections. CEO isn’t taking a pay cut though. Morons got a winning lottery ticket in the pandemic and assumed they’d keep winning every year.

    • Kongar@lemmy.dbzer0.com
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      I know they funded moderna - they basically built Moderna’s new plants including their cmo’s plant so that they could produce at scale. Govt built and funded the plants at risk - prior to fda approval - so that it massively sped up the process to getting the drug in people’s hands. Those plants are now used for other drugs.

      I think - but not 100% sure - Pfizer did it on their own.

      Still - 10,000% is shameful.

    • BrianTheeBiscuiteer@lemmy.world
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      I’m fine with the public-private partnership but money like this needs to come with strings attached. We should’ve made an agreement to cap the price. We developed these drugs under the Trump administration so I really don’t think the impact to poor and middle class citizens has ever been a thought in his mind.

    • eskimofry@lemmy.world
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      Much better strategy: you take the medicine… survive… and refuse to pay in protest. Sure, you might get sued for non-payment of bills… then a bunch of people can fight a class action lawsuit against pfizer.

    • vacuumflower@lemmy.sdf.org
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      had my blood oxygen drop as low as 79

      Oh, my aunt’s husband was in this situation. And they live in Armenia, where normal Covid treatment was, is and will be virtually nonexistent.

      He’s thankfully alive and didn’t lose any of his wits.

    • PilferJynx@lemmy.world
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      I get the anger. We really need to fully socialize these medical development centers. But on the other hand, they did most of the work. They didn’t have to.

      • Raiderkev@lemmy.world
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        I’m sure the research was publicly funded, and the profit will be private as is tradition.

      • I_Fart_Glitter@lemmy.world
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        Yep, that Pfizer for you, using taxpayer money to R&D drugs they will use to price gouge the public who paid for it, out of the kindness of their hearts.

    • givesomefucks@lemmy.world
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      I’ll never understand why so many people think middlemen somehow makes shit cheaper…

      Taxes > government research > cheap meds

      With the bonus point of no more pharmaceutical companies selling shit like oxy for profit

      • VinnieFarsheds@lemmy.world
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        1 year ago

        Because they think government is inefficient by default, and a commercial business is motivated towards max efficiency to cut costs. Maybe all of this is true, but in capitalism companies also sell for the optimal price based on price elasticity. No competitors + essential live saving product = high prices.

        • vacuumflower@lemmy.sdf.org
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          Actually in human societies, not just in capitalism.

          People talk about capitalism being bad as if only there people try to eat each other to become richer.

          If you read something about reasons the USSR wouldn’t have more efficient centralized planning, while having necessary machinery and resources, or why it wouldn’t have standardized something, while having the standardization apparatus and planned economy, or why all the Internet-like projects went nowhere in USSR while being much more ambitious due to, again, planned economy, or why despite less fragmentation scale wouldn’t make things cheaper to produce in USSR, but the opposite, and so on - that’s because every reform would mean someone losing influence, and that someone would naturally use that influence to resist reform.

          It’s actually fascinating to read how some of those people really believed in Marxism and Communism, and were even very competent sometimes, but the general architecture made the whole thing less than just a sum of its parts. Really sad, though.

          • Maggoty@lemmy.world
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            I agree that the problems aren’t just in Capitalism. However, the country with the unofficial historical tagline, “and then it got worse”, may not be the best example. I think China is a really good example of influence peddling outside a free market.

            • vacuumflower@lemmy.sdf.org
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              Well, China, when its ruling organization still had some consistent ideology, was a copy of Stalin’s USSR, bigger and weaker, give or take. Only it started later.

              Its way off that track started with reforms like Kosygin’s reforms, would those not be neutered.

              I’d say the reason in China this happened was exactly that it was bigger and weaker. It didn’t quite have anything like Soviet industrial establishment, and it had the issues of poverty, hunger etc.

      • vacuumflower@lemmy.sdf.org
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        Because “government research” doesn’t cover mass production and all of the supply chain management. Which is where anything bureaucratic really sucks.

        (Unless you need to build things badly, but fast and on large scale, mobilization-style - see Khruschev-era mass construction in ex-USSR, or, for exotic stuff, older state-built housing in Israel which isn’t that much better).

        Actual production rots very quickly, if centralized and bureaucratic.

        I agree that research requires long-term investment and is in general a completely different thing.

        • givesomefucks@lemmy.world
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          There’s just so much wrong in your comment I can’t address it all…

          But where has anyone said the government had to manufacture it too?

          We’re talking about patents right now.

          The rest of what you said is still wrong, can’t stress that enough, it just also has absolutely nothing to do with what people were talking about…

          • vacuumflower@lemmy.sdf.org
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            There’s just so much wrong in your comment I can’t address it all…

            If you can’t then you’d better say nothing.

            But where has anyone said the government had to manufacture it too?

            You said when talking about pharma companies as middlemen. You remove those middlemen - you have to do tasks they perform.

            We’re talking about patents right now.

            Yes, patent law should be abolished. That’s what I’m talking about while commenting in most threads blaming “capitalism”, because in like 2/3 cases patent law is to blame and not that.

            The rest of what you said is still wrong, can’t stress that enough, it just also has absolutely nothing to do with what people were talking about…

            Thank you for your unsubstantiated opinion which I can beat with that of my own every time, so not sure why you’d even express it without details.

            • givesomefucks@lemmy.world
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              If you can’t then you’d better say nothing.

              You’ve got a point, I should have said “won’t put the effort in”.

              I looked at your profile, you wait till posts are really old, then spam a bunch of nonsensical replies in it.

              I’m just gonna block you. Everyone wins.

              • vacuumflower@lemmy.sdf.org
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                I’m just gonna block you. Everyone wins.

                Not the worst way to look at this, if you want my opinion.

    • FlashMobOfOne@lemmy.world
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      People vote for it every two years and are shocked, just shocked when they get precisely what they voted for.

      • eskimofry@lemmy.world
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        Do you think pfizer and other companies who spend hundreds of millions lobbying would be like “aww shucks! the public voted to curb our shitty behavior, let’s go home!”?

    • vacuumflower@lemmy.sdf.org
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      Ah, trademark laws and patents are obviously governmental stuff. So - not present in some imagined absolute capitalism. And with those abolished (except for stealing authorship still being illegal), I suppose market mechanisms would do their job sufficiently well for this particular case.

      Believing in capitalism is believing in humans making rational and moral choices, anyone to do that would be nuts. That’s a proactive answer to politically active people getting triggered by my comment and labeling me as a member of the other crowd.

  • LostWon@lemmy.ca
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    So many Martin Shkrelis out there pricing drugs to the highest level they can get away with. Every big pharmaceutical company does this kind of thing, especially with new drugs.

  • Alien Nathan Edward@lemm.ee
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    It’s been too long since the aristocrats were reminded that they need us more than we need them and that they can’t hire enough of us to stop the rest of us once we take an idea to mind.

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    Seriously, people are acting like this is new. There is no sense in shaming them we’ve had it brought to the mainstream by people like Martin Skhreli and nothing has been done. Martin Skhreli himself is only in jail because of his ponzi schemes, a.k.a. screwing other rich people out of their money. The only reason Pfizer was praised was because it was needed in a time of need and because they hired plenty of lobbyists.

    • postmateDumbass@lemmy.world
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      Ive accepted this behavior as typical and standard issue human nature.

      That is why i am mot having kids, seeing that extinction is the best future for humans. Evolution puts any other intelligence in the universe at risk.

  • some_guy@lemmy.sdf.org
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    I was given (free) Paxlovid when I finally contracted covid this year. We need laws regulating price increases. If you can’t demonstrate that your costs for a product or service went up, you can’t increase by more than x%. I don’t know how you do this without encouraging higher introductory prices because it’s not a problem that I’ve thought about in depth, but something like this needs to happen with further consideration.

    Another thing I’d like to see is robber barons getting prosecuted for crimes against humanity, but that’s not realistic.

    • Modern_medicine_isnt@lemmy.world
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      Yeah, that doesn’t really work. Because they will always find a way to make costs go up, and then demonstrate it. Auditing such things would benearly impossible. The only real solution is for certain industries to be nonprofits. Healthcare really shouldn’t be about profit, it should ge about care.

    • ILikeBoobies@lemmy.ca
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      Just get rid of copyright, let the person who can create your product the cheapest make money off it

      Or would that be too capitalist for the US

      • Alien Nathan Edward@lemm.ee
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        I think you’re thinking of patents rather than copyright. I was about to ask something snarky like “without the ability to patent their discoveries what would cause these drug companies to pay for r&d up front?” but honestly, this one was paid for by government grants anyway and that’s really where my problem comes in. We seem to have developed this amazing worst of both worlds where the public bears all the up front expense of r&d and then the government just gives away what we bought for ourselves so that they can raise the price to 100x what the medication actually costs.

        • ILikeBoobies@lemmy.ca
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          I was just being lazy and didn’t write patents and trademarks all together

          I figured saying copyright would be enough for people to include the whole copyright office

          • Alien Nathan Edward@lemm.ee
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            Patents, trademarks and copyrights are three entirely different things. Patents cover products for sale, and give an inventor the exclusive right to manufacture an invention for a given time. Trademarks cover branding, and allow the person registering the trademark to prevent anyone else from using it or something a reasonable person could confuse with it indefinitely. Copyright is exclusively for intellectual property and allows the copyright holder to stop anyone from making copies of their work, derivatives of their work or work that is substantially similar to their work.

            • FatCrab@lemmy.one
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              This is very incorrect except for the very high level. Patents cover systems and methods and devices that are more than mere physical phenomena. Patent owners are granted an exclusive monopoly over the implementation of what the patent issued on (i.e., its eventual claims) that runs up to 20 years from the time of filing. They are an intellectual property right premised in property theory.

              Trademarks cover designators of origin. Fundamentally, they are to reduce consumer confusion and are ultimately nothing more than a presumption once granted in favor of the owner in unfair competition disputes. They are also an intellectual property but are premised in totally different theories of law and can apply to literally anything that can be strongly associated with a company, more or less.

              Copyright is an intellectual property, yes, but is limited to creative expression fixed in a tangible medium. This is a very short sentence but has some pretty serious depth to it. Copyright is ultimately a very specific type of right to, and this may shock you, copying a thing (fixed in a tangible medium…you do not have copyright on ideas).

              That all said, pharma patents and, really, industry as a whole is super fucked and needs serious reimagining in the current era. But some form of IP absolutely is necessary to incentivize and enable drug creation of it is to persist in our free market capitalist economic structure.

      • xenspidey@lemmy.zip
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        1 year ago

        So you spend hundreds of thousands of dollars creating and testing a new drug to cure something. Then another company can come along and undercut you since they didn’t spend the upfront money. And now you go bankrupt? How is that fair? I’m not saying Big Pharma isn’t an issue but as always, the solution is somewhere in the middle.

          • xenspidey@lemmy.zip
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            1 year ago

            Then there will be no new medicines, companies will not be able to afford to pay the scientists.

            • Cosmic Cleric@lemmy.world
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              1 year ago

              Then there will be no new medicines, companies will not be able to afford to pay the scientists.

              That would not be true if the government funded things.

              I really wish we didn’t let Capitalism control vital to our living services.

              • xenspidey@lemmy.zip
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                1 year ago

                Why on earth would we want the government funding and running things, that would be a nightmare. Government is far too big as it is now.

                • aliteral@lemmy.world
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                  1 year ago

                  To be fair, I come from a country where we have free healthcare, free education up to college level (we only pay when taking masters or things like that, after finishing our chosen career. Our most know public university is pretty top notch if we talk about content and education quality. And our healthcare is pretty good too, although there is also private healthcare and education. In the education department, at least to my knowledge, there is not really a difference. The USA is not big. It spends a lot on defense (which usually use to wage innecesary wars or disrupt other governments) and maybe too much in mantaining this horrible two party system you’ve got. That said, my country’s economy is in very bad shape (Argentina has inflation rates that are sky high).

                • Cosmic Cleric@lemmy.world
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                  1 year ago

                  Why on earth would we want the government funding and running things

                  I’ll take competency issues over greed and harm anytime.

            • ILikeBoobies@lemmy.ca
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              1 year ago

              Guess they’d be stuck with relying on research grants and finding cheaper ways to combat diseases

              • FatCrab@lemmy.one
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                1 year ago

                No, they would just keep everything trade secret and we’d have no idea how to replicate the medicine.

  • Nobody@lemmy.world
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    1 year ago

    Don’t ever think for a second that pharmaceutical companies did anything during Covid for our benefit. They were working their actuarial tables to figure out how they maximize their profits in the future against sick people dying.

  • db2@sopuli.xyz
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    1 year ago

    And who is in charge of making sure this kind of immoral illegal thing doesn’t happen? People who are still somehow allowed to collect kickbacks in exchange for looking the other way.

    • Redrum714@lemm.ee
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      1 year ago

      It does make companies more willing to invest more into drug research , which is a good thing.

      • Maggoty@lemmy.world
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        1 year ago

        Drug research is overwhelmingly publicly funded. Private R&D is a PR myth we were fed to justify high prices.

          • Maggoty@lemmy.world
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            1 year ago

            No. Those two statements don’t go together like that. They aren’t making big new drugs. At most they are looking for ways to adjust the formula so they can extend patents. There is no amount of profit that makes them willing to do more R&D.

      • Sunforged@lemmy.ml
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        1 year ago

        Covid treatment was publicly funded. This is a case of public funding going to research and private companies profiting from it.

        Everyone should be outraged from the situation. This cheap treatment is being denied to the majority of the world’s population because of patients, and so covid has more opportunities to mutate and make everyone less safe.

      • twopi@lemmy.ca
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        1 year ago

        Why don’t we just take investor money and invest in it ourselves?

        Others have already pointed out that the covid vaccine was publicly funded ergo the benefit should be publicly owned